2015年12月1日星期二

A Brief History of Antibacterial

 
          In the 17th century, Antonie Van Leeuw came from Netherlands, who is the first man to observe the existence of bacteria. Over the next 200 years, the death rate of mankind was extremely high due to bacterial infection. Until 1941s, the discovery of penicillin was the unique antidote to save people against bacteria at that period. There is no doubt that this is a world-shaking innovation in the medical history. The thriving golden age of antibiotics is coming. However, in the 1950s and 1960s, there were at most 7 million people died of bacterial infection due to the massive application of antibiotics, although, at the end of the 20th century, the amount of people died for infection relapsed to 20 million due to the increase of drug-resistant bacteria. “Survival of the fittest.” -- It only takes 2-3 years for bacteria to become drug-resistant character, while for scientists, it will take at least 5-10 years or even longer time to develop a new antibiotic.
          
          In 2014, WHO has launched the “Antimicrobial resistance: global report on surveillance”, which declared the coming of the “post-antibiotic era”. The only super weapon in the hands of the human being is to lose its power gradually.
          
          The severe reality and the rapid development of life science and technology, make our relationship between human and bacteria to be reviewed, and a new recognition to be established gradually. There is no doubt that bacteria is an important participant of human’s physiological functions, rather than a thorough destroyer.
         
          It was found in many studies recently that the concomitant bacterial invasion into human body starts with the bacteria colonization on the surface of interventional devices or implants, upon which the bacterial aggregations were built, and then the bacteria produce secretion from which the biofilm evolves. Once an infection source arises, as soon as the biofilm forms, it's overwhelmingly difficult to kill the bacteria wrapped by the biofilm, and human immune system or any medicine will not work on this. This is one of the powerful survival strategies for the natural evolution of bacteria against bad environment.
         
          RYAN antibacterial technology comes forth with the different solutions to decrease the infection risk and reduce the damage of normal tissue. We are not to "rude" to kill the bacteria as a means of confrontation, but to reduce the damage of environment and keep the balance of nature. Don’t give the drug resistant bacteria opportunity to fully dominant in nature. As a guide, we have developed the following technology platforms and products: CleanSur™ ; CleanFab™ and CleanMed™.


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